The prefrontal cortex: Projection area of the thalamic mediodorsal nucleus?
نویسندگان
چکیده
The historical bases of the definitions of the prefrontal cortex are reviewed (cytoarchitecture, electrical unexcitability, afferents from the mediodorsal thalamic nucleus). Evidence is presented that the widely accepted proposal of Rose and Woolsey (1948) to name all cortex prefrontal that is reached by afferents from the mediodorsal nucleus is questionable for three reasons: the diversity of cortical fields reached by the mediodorsal nucleus, the overlapping of thalamic projections, and the possibility of a columnor band-like thalamocortical organization. An alternative approach to a definition of the prefrontal cortex is suggested.
منابع مشابه
Cortical projections of the thalamic mediodorsal nucleus in the rat. Definition of the prefrontal cortex.
Deposits of somatopetal tracers, that filled the entire dorsolateral cortex of one hemisphere, labelled only a few cell bodies in the thalamic mediodorsal nucleus (MD). Further experiments served to confirm the existence of strong projections from MD to the mesial and suprarhinal areas of the frontal cortex. Thus, only a very small proportion of the MD neurones in the rat projects outside the c...
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